Kidney and smooth muscle

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Kidney and smooth muscle

Jump to navigation Jump to search Not to be confused with granule cell.

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Please help to improve this article by introducing more precise citations. May Juxtaglomerular cell Microscopic image of juxtaglomerular cells Drawing of renal corpuscle: Macula densa cells are labeled 7, extraglomerular mesangium are labeled 5b.

They are specialized smooth muscle cells mainly in the walls of the afferent arteriolesand some in the efferent arterioles, that deliver blood to the glomerulus.

In synthesizing renin, they play a critical role in the renin—angiotensin system and thus in autoregulation of the kidney.

Kidney and smooth muscle

Juxtaglomerular cells secrete renin in response to a drop in pressure detected by stretch receptors in the vascular walls, or when stimulated by macula densa cells. Macula densa cells are located in the distal convoluted tubule, and stimulate juxtaglomerular cells to release renin when they detect a drop in sodium concentration in tubular fluid.

Together, juxtaglomerular cells, extraglomerular mesangial cells and macula densa cells comprise the juxtaglomerular apparatus. In appropriately stained tissue sections, juxtaglomerular cells are distinguished by their granulated cytoplasm. The juxtaglomerular cell is a cell that is located near the glomerulus, hence its name.

Practice Quiz: Urinary System Anatomy and Physiology

When stimulated by epinephrine or norepinephrinethese receptors induce the secretion of renin. These cells also respond directly to a decrease in systemic blood pressure which is manifested as a lower renal perfusion pressure.Smooth muscle differentiation and patterning is a fundamental process in urinary bladder development that involves a complex array of local environmental factors, epithelial-mesenchymal interaction, and signaling pathways.

Contractile proteins of smooth muscle type were found in kidney cells by immunological methods. The reactions of rabbit anti-actin, anti-heavy meromyosin and anti-myosin antisera with rat kidney were investigated by immunoelectron microscopy.

Medications that relax ureteral smooth muscle to help pass ureteral stones have been proposed for decades. 8 Prior to , however, only 1 randomized controlled trial (RCT) of medical therapy for ureteral stones had been published.

9 A subsequent meta-analysis found 9 studies and showed that medical therapy did increase the chances that a. External Anatomy.

The left kidney is located at about the T12 to L3 vertebrae, whereas the right is lower due to slight displacement by the liver.

SIU SOM Histology GI

Emerging from the hilum is the renal pelvis, which is formed from the major and minor calyxes in the kidney. The smooth muscle in the renal pelvis funnels urine via peristalsis into the ureter.

Kidney tumor - Adult cystic nephroma.

The vagina provides an instructive contrast with the esophagus. The vagina and the esophagus are both tubular organs with a mucosa lined by non-keratinized stratified squamous epithelium. Hence these two organs appear superficially similar. However, bundles of smooth muscle are interwoven with connective tissue throughout the wall of the vagina, so that there is no clear demarcation of. Oct 28,  · Multisystemic smooth muscle dysfunction syndrome is a disease in which the activity of smooth muscle throughout the body is impaired. This leads to widespread problems including blood vessel abnormalities, a decreased response of the pupils to light, a weak bladder, and weakened contractions of the muscles used for the digestion of food (hypo peristalsis). The term smooth muscle refers to a muscle of the human body that is part of a involuntary muscle group. These muscles are extremely important to help the body perform a variety of crucial tasks, and can be found in many parts of the body.

Cysts lined by flat / cuboidal / hobnail cells separated by fibrous septa that may have an ovarian stroma-like appearance or can be pauicellular.

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Angiomyolipoma of the Kidney –